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  • EFFICACY & SAFETY
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  • EFFICACY & SAFETY
    • CLINICAL TRIAL RESULTS
    • SAFETY
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PRIVACY POLICY

Tolmar is committed to protecting your personal privacy. We handle personal information with the utmost respect and assure that all information submitted on the Tolmar site will remain strictly confidential. Tolmar requires that any person or organization providing products and/or services to our clients on our behalf protect the confidentiality of Tolmar’s customer information.

 

Unless Tolmar receives written permission from an individual, we will not:

  • Sell or rent personal information;
  • Provide personal information to persons or organizations outside of Tolmar and our affiliate business partners; 
  • Market personal information to the general public.

 

The Tolmar site collects only information provided “voluntarily” when using or registering with us on this site. Such information may include:

  • Your Name
  • Position/Job Title
  • Company Name
  • Street Address
  • City and State
  • ZIP Code
  • Telephone Number
  • Email Address

 

The information gathered from each client is used internally to process proposals, ensure proper billing, service an account and offer other employment related products that may better serve your needs. 

Applicability of This Policy

This privacy policy applies only to the information that is collected on Tolmar’s website. It does not apply to any information collected through other methods or sources, including sites owned or operated by our affiliate business partners.

Affiliated Business Partners

Tolmar works closely with affiliated businesses partners that may have links on our website. Please remember that when you use a link to go from Tolmar’s website to another website, our Privacy Policy no longer applies.

 

Any browsing and interaction on any third party’s website, including any site that has a link on Tolmar’s website, is subject to the policies and rules of that website.

Changes to Policy Statement

Tolmar reserves the right to change, modify, or amend our privacy policy as needed; we intend to maintain a policy that is at the forefront of privacy and security principles. Tolmar takes privacy matters seriously; if there are any changes to our privacy policy statement, we will place an updated version on this page. Tolmar encourages site users and visitors to check our privacy policy regularly to stay informed of any policy updates or changes.

Contact Information

Thank you for choosing Tolmar. We appreciate your business and the opportunity to serve you. 
If you have any questions, concerns or comments regarding this privacy policy, please feel free to contact Tolmar at: 
 
Tolmar, Inc

701 Centre Ave

Fort Collins, CO 80526

970-212-4500

1-877-4Tolmar (1-877-486-5627) 

California Residents

If you are a California resident, the information below may apply to you in addition to our Privacy Policy. This below information uses certain terms that have the meanings given to them by the California Consumer Privacy Act.  

We only share your personal information with the categories of third parties for the business and commercial purposes described below. We do not sell or rent personal information to third parties, including for their own marketing purposes.

Collection and Disclosure

During the past 12 months, we may have:
a.   Collected the following categories of personal information about you:

  • Identifiers: identifiers such as a real name, alias, postal address, unique personal identifier (such as customer number, unique pseudonym, or user alias), email address, account name, Social Security number, driver’s license number, passport number, and other similar identifiers, physical characteristics or description, state identification card number, and signature
  • Identifiers (Online): a device identifier; cookies, beacons, pixel tags, mobile ad identifiers and similar technology; other forms of persistent or probabilistic identifiers, and Internet Protocol address
  • Other Financial, Medical, and Health Information: bank account number, credit card number, debit card number, insurance policy number, and other financial information, medical information, and health insurance information
  • Information Related to Characteristics Protected Under California or Federal Law: characteristics  of protected classifications under California or federal law, such as race, color, national origin, religion, age, sex, gender, gender identity, gender expression, sexual orientation, marital status, medical condition, ancestry, genetic information, disability, citizenship status, and military and veteran status
  • Commercial Information: including records of personal property, products or services purchased, obtained, or considered, and other purchasing or consuming histories or tendencies
  • Biometric Information: Physiological, biological or behavioral characteristics that can be used alone or in combination with each other to establish individual identity, including DNA, fingerprint, diagnostic or lab results, imagery of the face from which an identifier template can be extracted, and sleep, health, or exercise data that contain identifying information.
  • Internet and Other Electronic Network Activity Information: including, but not limited to, browsing history, search history, and information regarding your interaction with websites, applications or advertisements
  • Geolocation Data: Precise geographic location information about a particular individual or device.
  • Sensory Information: Audio, electronic, visual, thermal, and similar information
  • Professional or Employment-Related Information 
  • Education Information
  • Profile Inferences: inferences drawn from any of the information identified above to create a profile about you reflecting your preferences, characteristics, psychological trends, predispositions, behavior, attitudes, intelligence, abilities, and aptitudes

b.   Collected personal information about you for the following business or commercial purposes:

  • to respond to your inquiries and to fulfill your requests;
  • to send you important information regarding our relationship with you or regarding this website, changes to our terms, conditions, and policies and/or other administrative information;
  • for audits, to verify that our internal processes function as intended and are compliant with legal, regulatory, or contractual requirements;
  • for fraud or crime prevention, and for technical security monitoring purposes;
  • to facilitate the development of new products and services;
  • to enhance, improve or modify our website or products and services;
  • for data analysis that will allow us to understand website usage trends;
  • to determine the effectiveness of our promotional campaigns, so that we can adapt our campaigns to the needs and interests of our users.
  • to better understand you, so that we can personalize our interactions with you and provide you with information and/or offers tailored to your interests
  • to comply with and enforce applicable legal requirements, relevant industry standards and our policies

c.     Shared your personal information with the following categories of third parties:

  • Our affiliates
  • Our joint marketing partners
  • Our business partners
  • Social media networks
  • Third-party marketing partners
  • Government entities

d.     Disclosed for a business purpose the following categories of personal information about you:

  • Identifiers
  • Identifiers (Online)
  • Other Financial, Medical and Health Information
  • Information Related to Characteristics Protected Under California or Federal Law
  • Commercial Information
  • Biometrics
  • Internet and Other Electronic Network Activity Information
  • Geolocation Data
  • Sensory Information
  • Professional or Employment-Related Information
  • Education Information
  • Profile Inferences
California Consumer Privacy Rights

Subject to certain exceptions, California residents have the right to make the following requests, at no charge, up to twice every 12 months:

  • Copy:  You may request a copy of the specific pieces of personal data that we have collected about you in the prior 12 months and to have this delivered, free of charge, either (a) by mail or (b) electronically in a portable and, to the extent technically feasible, readily useable format that allows you to transmit this information to another entity without hindrance.
  • Deletion:  You may request deletion of your personal data that we have collected about you.
  • Know:  You may request that we provide you certain information about how we have handled your personal data in the prior 12 months, including the:
    • categories of personal data collected;
    • categories of sources of personal data;
    • business and/or commercial purposes for collecting your personal data;
    • categories of third parties/with whom we have disclosed or shared your personal data; and
    • categories of personal data that we have disclosed or shared with a third party for a business purpose.
 

We will not discriminate against you for exercising these rights.

Submitting Requests. To exercise your rights please submit a request, or have an authorized agent submit a request on your behalf, to info@tolmar.com or call the following toll-free telephone number 1-844-4TOLMAR. We will respond to your request consistent with applicable law.

Tap for safety information

INDICATION AND IMPORTANT SAFETY INFORMATION

INDICATION

RUBRACA® (rucaparib) is indicated for the treatment of adult patients with a deleterious BRCA mutation (germline and/or somatic)-associated metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor-directed therapy and a taxane-based chemotherapy. Select patients for therapy based on an FDA-approved companion diagnostic for RUBRACA. 

This indication is approved under accelerated approval based on objective response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. 

SELECT IMPORTANT SAFETY INFORMATION

Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML) occur in patients treated with RUBRACA, and are potentially fatal adverse reactions. In 1594 treated patients with ovarian cancer, MDS/AML occurred in 32 patients (2%), including those in long term follow-up. Of these, 14 occurred during treatment or during the 28-day safety follow-up (0.9%). The duration of RUBRACA treatment prior to the diagnosis of MDS/AML ranged from < 2 months to approximately 72 months. The cases were typical of secondary MDS/cancer therapy-related AML; in all cases, patients had received previous platinum-containing chemotherapy regimens and/or other DNA damaging agents. 

In ARIEL3, of patients with a germline and/or somatic BRCA mutation treated with RUBRACA, MDS/AML occurred in 9 out of 129 (7%) patients treated with RUBRACA and 4 out of 66 (6%) patients treated with placebo. The duration of therapy with RUBRACA in patients who developed secondary MDS/cancer therapy-related AML varied from 1.2 to 4.7 years.

In TRITON2, MDS/AML was not observed in patients with mCRPC (n=209) regardless of homologous recombination deficiency (HRD) mutation.  
Do not start RUBRACA until patients have recovered from hematological toxicity caused by previous chemotherapy (≤ Grade 1). Monitor complete blood counts for cytopenia at baseline and monthly thereafter for clinically significant changes during treatment. For prolonged hematological toxicities (> 4 weeks), interrupt RUBRACA or reduce dose and monitor blood counts weekly until recovery. If the levels have not recovered to Grade 1 or less after 4 weeks or if MDS/AML is suspected, refer the patient to a hematologist for further investigations, including bone marrow analysis and blood sample for cytogenetics. If MDS/AML is confirmed, discontinue RUBRACA.  
Based on findings from genetic toxicity and animal reproduction studies, RUBRACA can cause fetal harm. Advise male patients with female partners of reproductive potential or who are pregnant to use effective methods of contraception during treatment and for 3 months following last dose of RUBRACA. Advise male patients not to donate sperm during therapy and for 3 months following the last dose of RUBRACA. 

Most common adverse reactions of patients with BRCA-mutated mCRPC in TRITON2 (≥ 20%; Grade 1-4) were fatigue/asthenia (62%), nausea (52%), anemia (43%), AST/ALT elevation (33%), decreased appetite (28%), rash (27%), constipation (27%), thrombocytopenia (25%), vomiting (22%), and diarrhea (20%).  

Concomitant administration of RUBRACA with CYP1A2, CYP3A, CYP2C9, or CYP2C19 substrates can increase the systemic exposure of these substrates, which may increase the frequency or severity of adverse reactions of these substrates. If concomitant administration is unavoidable between RUBRACA and substrates of these enzymes where minimal concentration changes may lead to serious adverse reactions, decrease the substrate dosage in accordance with the approved prescribing information.  
If concomitant administration with warfarin (a CYP2C9 substrate) cannot be avoided, consider increasing the frequency of international normalized ratio (INR) monitoring.  
For medical information inquiries within the U.S., contact pharma& at medinfo.us@pharmaand.com. 
You may report adverse events to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Alternatively, to report an adverse event or reaction, contact pharma& by calling 1-800-506-8501 or emailing pv@pharmaand.com.
To report a product complaint, contact pharma& at complaints@pharmaand.com. 
Please see full Prescribing Information for RUBRACA.
Tolmar Inc logo
The individuals pictured in this site are models, and the images are being used for illustrative purposes only.

©2024 Tolmar, Inc. All rights reserved. Tolmar, ELIGARD, increMENtal, and their associated logos are trademarks of the Tolmar Group. Third-party trademarks and product names belong to their respective owners. RUBRACA® is a registered trademark of pharma& Schweiz GmbH, used under license by Tolmar. TPI.2024.eng.4475.v1 12/24

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  • EFFICACY & SAFETY
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